The intent of the FY20 PRARP LEAP-InCASA is to support innovative and impactful research that improves the quality of life and care for individuals, families and care providers living with the common symptoms of TBI and/or AD/ADRD as related to the PRARP’s mission (see Section II.A, Program Description).

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The proposed work should innovatively challenge existing research paradigms or exhibit high levels of creativity within the contexts of the PRARP’s mission and vision.

This can include innovations and research for symptom reduction (e.g., cognitive, behavioral, function, mood), resiliency factors, increasing or maintaining independence, and support for families and care providers.

The FY20 PRARP LEAP-InCASA supports multi-institutional, harmonized research initiatives.

As such, applications to the FY20 PRARP LEAP-InCASA require a Coordinating Center and a minimum of two Partnering Sites, representing three separate institutions within the application package.

While the Coordinating Center provides overall infrastructure and support, each Partnering Site should develop its own unique research initiative that will be part of the overall project.

While each Partnering Site will develop its own unique research initiative, the overall project must focus on a single symptomatology category as described later in this section.

The application should also demonstrate the study team’s experience in both TBI and/or AD/ADRD research, as appropriate.

Given the patient-centered intent of the FY20 PRARP LEAP-InCASA, animal research is prohibited.